Gene therapy in oral cancer: A review

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Review Article

Author Details : Joseph Johny*, Sinitha Sreedhar, Rohini S Nair, Liz Megha I J, Vidya Sankar V B

Volume : 12, Issue : 1, Year : 2022

Article Page : 5-8

https://doi.org/10.18231/j.adr.2022.002

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Abstract

Gene therapy is the utilization of DNA as a specialist to treat illness. Gene therapy focuses on the inclusion of a functional gene into the cells of a patient for the rectification of an inborn error of metabolism, to change or fix a procured hereditary irregularity, and to give new capacity to the cell. Today, vast majority of the gene therapy studies are focused on malignant growth and inherited diseases which are connected to hereditary deformities. Malignant growth typically happens because of the creation of various mutations in a solitary cell which makes it proliferate wildly. A few techniques like surgery, radiation treatment, and chemotherapy have been utilized generally to treat tumors, yet recurrence is normal in roughly 33% of patients. To further develop the therapy methodology and to expand the endurance rate, gene therapy can be utilized as an aid to different treatments for malignant growth in patients. The reason for this article is to audit the ideas and strategy, with a knowledge into the ebb and flow research on its applications in oral squamous cell carcinoma (OSCC).
 

Keywords: Gene therapy, Oral cancer, Vectors, Gene gun

How to cite : Johny J, Sreedhar S, Nair R S, Liz Megha I J, Vidya Sankar V B, Gene therapy in oral cancer: A review. Arch Dent Res 2022;12(1):5-8

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